Aurigene and Forest Laboratories to collaborate on Development of Novel Oral Therapeutics for Obesity and Metabolic Disorders
Released on = February 1, 2007, 11:24 pm
Press Release Author = Aurigene Discovery Technologies Limited and Forest Laboratories, Inc.
Industry = Biotech
Press Release Summary = Aurigene Discovery Technologies, Ltd (Aurigene), a Bangalore-based discovery services company and Forest Laboratories Holdings, Ltd., a wholly owned subsidiary of Forest Laboratories, Inc. (NYSE: FRX) announced today that the two companies have entered into a collaboration agreement to discover small molecule drug candidates for a novel obesity and metabolic disorders target
Press Release Body = BANGALORE, India and NEW YORK, January 30, 2007-- Aurigene Discovery Technologies, Ltd (Aurigene), a Bangalore-based discovery services company and Forest Laboratories Holdings, Ltd., a wholly owned subsidiary of Forest Laboratories, Inc. (NYSE: FRX) announced today that the two companies have entered into a collaboration agreement to discover small molecule drug candidates for a novel obesity and metabolic disorders target. Forest selected the target and will direct the discovery collaboration. Under the terms of the agreement, Aurigene will undertake and fund discovery and optimization of lead compounds, with close participation by Forest's scientists. Forest will have responsibility for and will fund all subsequent drug development and commercialization activities. In addition, Forest has full ownership of the compounds developed under the collaboration with unencumbered worldwide rights. Forest will pay Aurigene undisclosed research milestones according to a pre-defined research plan, as well as sales milestones upon commercialization of compounds arising from the collaboration. Aurigene could receive over $60 million in development and sales milestone payments if a compound is successfully commercialized. "Aurigene has been rapidly developing its small molecule discovery capabilities through a number of ongoing programs at various stages of development," said CSN Murthy, CEO of Aurigene. "We are excited to leverage Forest's world class development capabilities and marketing expertise. We believe that our collaboration can flourish by bringing together the complimentary strengths from both organizations. This agreement further strengthens Aurigene's unique risk sharing model of drug discovery partnerships. We are happy to have the opportunity to work together with Forest."
Dr. Ivan Gergel, Senior Vice President of Scientific Affairs and President of the Forest Research Institute, commented: \"We look forward to working with Aurigene to discover novel drug candidates for the treatment of obesity and metabolic disorders. These conditions have significant unmet medical needs and we believe the target we have identified holds promise. Our collaboration with Aurigene is an example of the continued evolution of Forest's business model such that we are now establishing discovery research partnerships to identify innovative compounds and to secure worldwide rights to the resulting products. Our search for capable partners led us to work with Aurigene and we are looking forward to a productive relationship.\"
About Aurigene: Aurigene Discovery Technologies Limited is a Bangalore-based discovery services company focused on collaborative drug discovery with pharmaceutical and biotech companies on a risk-sharing basis. Aurigene has integrated discovery capabilities, from target to pre-clinical lead optimization, including in vitro and in vivo biology and medicinal chemistry expertise. Aurigene also has structural biology and fragment based drug design capabilities, with in-house crystallization (XRD) and Bio NMR (600 MHz) facilities. The company is engaged in a number of discovery collaborations and provides discovery chemistry and biology services to companies in the US and Europe.
About Forest Laboratories and Its Products Forest Laboratories (http://www.frx.com ) is a US-based pharmaceutical company dedicated to identifying, developing, and delivering products that make a positive difference in peoples\' lives. Forest Laboratories\' growing product line includes Lexapro(R) (escitalopram oxalate), an SSRI indicated for adults for the initial and maintenance treatment of major depressive disorder and for generalized anxiety disorder; Namenda(R) (memantine HCl), an N-methyl- D-aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe Alzheimer\'s disease; Benicar(R)* (olmesartan medoxomil), an angiotensin receptor blocker, and Benicar* HCT(R) (olmesartan medoxomil- hydrochlorothiazide), an angiotensin receptor blocker and diuretic combination product, each indicated for the treatment of hypertension; and Campral(R)* (acamprosate calcium), indicated in combination with psychosocial support for the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation. *Benicar is a registered trademark of Sankyo Pharma, Inc., and Campral is a registered trademark of Merck Sante s.a.s., subsidiary of Merck KGaA, Darmstadt, Germany.
Except for the historical information contained herein, this release contains \"forward-looking statements\" within the meaning of the Private Securities Reform Act of 1995. These statements involve a number of risks and uncertainties, including the difficulty of predicting FDA approvals, acceptance and demand for new pharmaceutical products, the impact of competitive products and pricing, the timely development and launch of new products and the risk factors listed from time to time in the Company's SEC reports, including the Annual Report on Form 10-K for the fiscal year ended March 31, 2006 and on Form 10-Q for the periods ended June 30, 2006 and September 30, 2006.
Web Site = http://www.aurigene.com
Contact Details = CSN Murthy CEO Aurigene Discovery Technologies Limited, 39-40, KIADB Industrial Area, Electronic City Phase II, Hosur Road, Bangalore 560 100, India
Tel: + 91 80 2852 1314, 2852 1316, 2852 8943 Fax:+ 91 80 2852 6285
murthy_csn@aurigene. com
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